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Single-Molecule Super-Resolution Microscopy Reveals Heteromeric Complexes of MET and EGFR upon Ligand Activation
Receptor tyrosine kinases (RTKs) orchestrate cell motility and differentiation. Deregulated RTKs may promote cancer and are prime targets for specific inhibitors. Increasing evidence indicates that resistance to inhibitor treatment involves receptor cross-interactions circumventing inhibition of one...
Autores principales: | Harwardt, Marie-Lena I.E., Schröder, Mark S., Li, Yunqing, Malkusch, Sebastian, Freund, Petra, Gupta, Shashi, Janjic, Nebojsa, Strauss, Sebastian, Jungmann, Ralf, Dietz, Marina S., Heilemann, Mike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215329/ https://www.ncbi.nlm.nih.gov/pubmed/32316583 http://dx.doi.org/10.3390/ijms21082803 |
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