Design, Synthesis, and Anticancer Evaluation of Novel Indole Derivatives of Ursolic Acid as Potential Topoisomerase II Inhibitors

In this study, a series of new indole derivatives of ursolic acid bearing different N-(aminoalkyl)carboxamide side chains were designed, synthesized, and evaluated for their in vitro cytotoxic activities against two human hepatocarcinoma cell lines (SMMC-7721 and HepG2) and normal hepatocyte cell li...

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Detalles Bibliográficos
Autores principales: Li, A-Liang, Hao, Yun, Wang, Wen-Yan, Liu, Qing-Song, Sun, Yue, Gu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215373/
https://www.ncbi.nlm.nih.gov/pubmed/32326071
http://dx.doi.org/10.3390/ijms21082876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215373/
https://www.ncbi.nlm.nih.gov/pubmed/32326071
http://dx.doi.org/10.3390/ijms21082876

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