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CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets

Sarcomas represent one of the most challenging tumor types to treat due to their diverse nature and our incomplete understanding of their underlying biology. Recent work suggests cyclin-dependent kinase (CDK) pathway activation is a powerful driver of sarcomagenesis. CDK proteins participate in nume...

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Detalles Bibliográficos
Autores principales: Kohlmeyer, Jordan L, Gordon, David J, Tanas, Munir R, Monga, Varun, Dodd, Rebecca D, Quelle, Dawn E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215455/
https://www.ncbi.nlm.nih.gov/pubmed/32344731
http://dx.doi.org/10.3390/ijms21083018