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Cytotoxicity of the Sesquiterpene Lactone Spiciformin and Its Acetyl Derivative against the Human Leukemia Cell Lines U-937 and HL-60

Spiciformin (1) is a sesquiterpene lactone with a germacrane skeleton that is found in two Tanacetum species endemic to the Canary Islands. In this study, the cytotoxicities of 1 and its acetyl derivative (2) were evaluated against human tumor cells. These sesquiterpene lactones were cytotoxic again...

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Detalles Bibliográficos
Autores principales: Saavedra, Ester, Estévez-Sarmiento, Francisco, Said, Mercedes, Eiroa, José Luis, Rubio, Sara, Quintana, José, Estévez, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215469/
https://www.ncbi.nlm.nih.gov/pubmed/32316340
http://dx.doi.org/10.3390/ijms21082782