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The Heat Shock Protein HSP70 Promotes Th17 Genes’ Expression via Specific Regulation of microRNA

T helper cells type 17 (Th17) are orchestrators of autoimmune conditions, including multiple sclerosis (MS), but mechanisms of Th17 pathogenicity remain unknown. MicroRNAs (miRNA) are known to control T cells. To understand the function of miRNA in Th17, we have established a T cell line, EL4-TCR(+)...

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Detalles Bibliográficos
Autores principales: Cwiklinska, Hanna, Cichalewska-Studzinska, Maria, Selmaj, Krzysztof W., Mycko, Marcin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215546/
https://www.ncbi.nlm.nih.gov/pubmed/32316658
http://dx.doi.org/10.3390/ijms21082823