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Genetic Interactions of Histone Modification Machinery Set1 and PAF1C with the Recombination Complex Rec114-Mer2-Mei4 in the Formation of Meiotic DNA Double-Strand Breaks

Homologous recombination is essential for chromosome segregation during meiosis I. Meiotic recombination is initiated by the introduction of double-strand breaks (DSBs) at specific genomic locations called hotspots, which are catalyzed by Spo11 and its partners. DSB hotspots during meiosis are marke...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Suzuki, Takuya, Li, Ke, Gothwal, Santosh K., Shinohara, Miki, Shinohara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215556/
https://www.ncbi.nlm.nih.gov/pubmed/32290544
http://dx.doi.org/10.3390/ijms21082679