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A Novel CD147 Inhibitor, SP-8356, Attenuates Pathological Fibrosis in Alkali-Burned Rat Cornea

The corneal fibrotic responses to corneal damage often lead to severe corneal opacification thereby resulting in severe visual impairment or even blindness. The persistence of corneal opacity depends heavily on the activity of corneal myofibroblast. Myofibroblasts are opaque and synthesize a disorga...

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Detalles Bibliográficos
Autores principales: Joung, Chanmin, Noh, Hyojin, Jung, Jeein, Song, Hwa Young, Bae, Hwanse, Pahk, Kisoo, Kim, Won-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215672/
https://www.ncbi.nlm.nih.gov/pubmed/32340317
http://dx.doi.org/10.3390/ijms21082990