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Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line

While two mouse NANOS paralogues, NANOS2 and NANOS3, are crucial for maintenance of germ cells by suppression of apoptosis, the mouse NANOS1 paralogue does not seem to regulate these processes. Previously, we described a human NANOS1 p.[(Pro34Thr);(Ser83del)] mutation associated with the absence of...

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Detalles Bibliográficos
Autores principales: Janecki, Damian M., Ilaslan, Erkut, Smialek, Maciej J., Sajek, Marcin P., Kotecki, Maciej, Ginter-Matuszewska, Barbara, Krainski, Patryk, Jaruzelska, Jadwiga, Kusz-Zamelczyk, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215683/
https://www.ncbi.nlm.nih.gov/pubmed/32344590
http://dx.doi.org/10.3390/ijms21083009