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Synovial Fluid Interleukin-16 Contributes to Osteoclast Activation and Bone Loss through the JNK/NFATc1 Signaling Cascade in Patients with Periprosthetic Joint Infection

Because of lipopolysaccharide (LPS)-mediated effects on osteoclast differentiation and bone loss, periprosthetic joint infection (PJI) caused by Gram-negative bacteria increases the risk of aseptic loosening after reimplantation. Synovial fluid interleukin-16 (IL-16) expression was higher in patient...

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Detalles Bibliográficos
Autores principales: Chang, Yuhan, Hsiao, Yi-min, Hu, Chih-Chien, Chang, Chih-Hsiang, Li, Cai-Yan, Ueng, Steve W. N., Chen, Mei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215706/
https://www.ncbi.nlm.nih.gov/pubmed/32326301
http://dx.doi.org/10.3390/ijms21082904