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Attenuation of the Diffuse Noxious Inhibitory Controls in Chronic Joint Inflammatory Pain Is Accompanied by Anxiodepressive-Like Behaviors and Impairment of the Descending Noradrenergic Modulation

The noradrenergic system is paramount for controlling pain and emotions. We aimed at understanding the descending noradrenergic modulatory mechanisms in joint inflammatory pain and its correlation with the diffuse noxious inhibitory controls (DNICs) and with the onset of anxiodepressive behaviours....

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Detalles Bibliográficos
Autores principales: Pereira-Silva, Raquel, Costa-Pereira, José Tiago, Alonso, Raquel, Serrão, Paula, Martins, Isabel, Neto, Fani L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215719/
https://www.ncbi.nlm.nih.gov/pubmed/32340137
http://dx.doi.org/10.3390/ijms21082973