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Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein

Dementia with Lewy bodies (DLB) is the second most prevalent neurodegenerative dementia after Alzheimer’s disease, and is pathologically characterized by formation of intracellular inclusions called Lewy bodies, the major constituent of which is aggregated α-synuclein (αS). Currently, neither a mech...

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Detalles Bibliográficos
Autores principales: Fujita, Masayo, Ho, Gilbert, Takamatsu, Yoshiki, Wada, Ryoko, Ikeda, Kazutaka, Hashimoto, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215759/
https://www.ncbi.nlm.nih.gov/pubmed/32325870
http://dx.doi.org/10.3390/ijms21082849