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Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein
Dementia with Lewy bodies (DLB) is the second most prevalent neurodegenerative dementia after Alzheimer’s disease, and is pathologically characterized by formation of intracellular inclusions called Lewy bodies, the major constituent of which is aggregated α-synuclein (αS). Currently, neither a mech...
Autores principales: | Fujita, Masayo, Ho, Gilbert, Takamatsu, Yoshiki, Wada, Ryoko, Ikeda, Kazutaka, Hashimoto, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215759/ https://www.ncbi.nlm.nih.gov/pubmed/32325870 http://dx.doi.org/10.3390/ijms21082849 |
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