P38α-MAPK Signaling Inhibition Attenuates Soleus Atrophy during Early Stages of Muscle Unloading

To test the hypothesis that p38α-MAPK plays a critical role in the regulation of E3 ligase expression and skeletal muscle atrophy during unloading, we used VX-745, a selective p38α inhibitor. Three groups of rats were used: non-treated control (C), 3 days of unloading/hindlimb suspension (HS), and 3...

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Detalles Bibliográficos
Autores principales: Belova, Svetlana P., Mochalova, Ekaterina P., Kostrominova, Tatiana Y., Shenkman, Boris S., Nemirovskaya, Tatiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215762/
https://www.ncbi.nlm.nih.gov/pubmed/32326654
http://dx.doi.org/10.3390/ijms21082756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215762/
https://www.ncbi.nlm.nih.gov/pubmed/32326654
http://dx.doi.org/10.3390/ijms21082756

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