A Computational Probe into the Structure and Dynamics of the Full-Length Toll-Like Receptor 3 in a Phospholipid Bilayer

Toll-like receptor 3 (TLR3) provides the host with antiviral defense by initiating an immune signaling cascade for the production of type I interferons. The X-ray structures of isolated TLR3 ectodomain (ECD) and transmembrane (TM) domains have been reported; however, the structure of a membrane-solv...

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Detalles Bibliográficos
Autores principales: Patra, Mahesh Chandra, Batool, Maria, Haseeb, Muhammad, Choi, Sangdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215789/
https://www.ncbi.nlm.nih.gov/pubmed/32325904
http://dx.doi.org/10.3390/ijms21082857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215789/
https://www.ncbi.nlm.nih.gov/pubmed/32325904
http://dx.doi.org/10.3390/ijms21082857

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