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The Case of the Scribble Polarity Module in Asymmetric Neuroblast Division in Development and Tumorigenesis
The Scribble polarity module is composed by Scribble (Scrib), Discs large 1 (Dlg1) and Lethal (2) giant larvae (L(2)gl), a group of highly conserved neoplastic tumor suppressor genes (TSGs) from flies to humans. Even though the Scribble module has been profusely studied in epithelial cell polarity,...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215838/ https://www.ncbi.nlm.nih.gov/pubmed/32325951 http://dx.doi.org/10.3390/ijms21082865 |