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The Case of the Scribble Polarity Module in Asymmetric Neuroblast Division in Development and Tumorigenesis

The Scribble polarity module is composed by Scribble (Scrib), Discs large 1 (Dlg1) and Lethal (2) giant larvae (L(2)gl), a group of highly conserved neoplastic tumor suppressor genes (TSGs) from flies to humans. Even though the Scribble module has been profusely studied in epithelial cell polarity,...

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Detalles Bibliográficos
Autor principal: Carmena, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215838/
https://www.ncbi.nlm.nih.gov/pubmed/32325951
http://dx.doi.org/10.3390/ijms21082865