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Cystic Fibrosis, CFTR, and Colorectal Cancer

Cystic fibrosis (CF), caused by biallelic inactivating mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, has recently been categorized as a familial colorectal cancer (CRC) syndrome. CF patients are highly susceptible to early, aggressive colorectal tumor development....

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Detalles Bibliográficos
Autores principales: Scott, Patricia, Anderson, Kyle, Singhania, Mekhla, Cormier, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215855/
https://www.ncbi.nlm.nih.gov/pubmed/32326161
http://dx.doi.org/10.3390/ijms21082891