Changing ALK-TKI-Resistance Mechanisms in Rebiopsies of ALK-Rearranged NSCLC: ALK- and BRAF-Mutations Followed by Epithelial-Mesenchymal Transition

Anaplastic lymphoma-kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) is prone to developing heterogeneous, only partly known mechanisms of resistance to ALK-tyrosine-kinase-inhibitors (ALK-TKIs). We present a case of a 38-year old male, who never smoked with disseminated ALK-rearranged (EM...

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Detalles Bibliográficos
Autores principales: Urbanska, Edyta M., Sørensen, Jens B., Melchior, Linea C., Costa, Junia C., Santoni-Rugiu, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215933/
https://www.ncbi.nlm.nih.gov/pubmed/32325863
http://dx.doi.org/10.3390/ijms21082847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215933/
https://www.ncbi.nlm.nih.gov/pubmed/32325863
http://dx.doi.org/10.3390/ijms21082847

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