GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route

Ganglioside GM1 (GM1) has been reported to functionally recover degenerated nervous system in vitro and in vivo, but the possibility to translate GM1′s potential in clinical settings is counteracted by its low ability to overcome the blood–brain barrier (BBB) due to its amphiphilic nature. Interesti...

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Detalles Bibliográficos
Autores principales: Di Biase, Erika, Lunghi, Giulia, Maggioni, Margherita, Fazzari, Maria, Pomè, Diego Yuri, Loberto, Nicoletta, Ciampa, Maria Grazia, Fato, Pamela, Mauri, Laura, Sevin, Emmanuel, Gosselet, Fabien, Sonnino, Sandro, Chiricozzi, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215935/
https://www.ncbi.nlm.nih.gov/pubmed/32325905
http://dx.doi.org/10.3390/ijms21082858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215935/
https://www.ncbi.nlm.nih.gov/pubmed/32325905
http://dx.doi.org/10.3390/ijms21082858

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