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GM1 Oligosaccharide Crosses the Human Blood–Brain Barrier In Vitro by a Paracellular Route
Ganglioside GM1 (GM1) has been reported to functionally recover degenerated nervous system in vitro and in vivo, but the possibility to translate GM1′s potential in clinical settings is counteracted by its low ability to overcome the blood–brain barrier (BBB) due to its amphiphilic nature. Interesti...
Autores principales: | Di Biase, Erika, Lunghi, Giulia, Maggioni, Margherita, Fazzari, Maria, Pomè, Diego Yuri, Loberto, Nicoletta, Ciampa, Maria Grazia, Fato, Pamela, Mauri, Laura, Sevin, Emmanuel, Gosselet, Fabien, Sonnino, Sandro, Chiricozzi, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215935/ https://www.ncbi.nlm.nih.gov/pubmed/32325905 http://dx.doi.org/10.3390/ijms21082858 |
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