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SGLT2 Inhibitor Empagliflozin and DPP4 Inhibitor Linagliptin Reactivate Glomerular Autophagy in db/db Mice, a Model of Type 2 Diabetes

Recent data have indicated the emerging role of glomerular autophagy in diabetic kidney disease. We aimed to assess the effect of the SGLT2 inhibitor empagliflozin, the DPP4 inhibitor linagliptin, and their combination, on glomerular autophagy in a model of type 2 diabetes. Eight-week-old male db/db...

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Detalles Bibliográficos
Autores principales: Korbut, Anton I., Taskaeva, Iuliia S., Bgatova, Nataliya P., Muraleva, Natalia A., Orlov, Nikolai B., Dashkin, Maksim V., Khotskina, Anna S., Zavyalov, Evgenii L., Konenkov, Vladimir I., Klein, Thomas, Klimontov, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215949/
https://www.ncbi.nlm.nih.gov/pubmed/32340263
http://dx.doi.org/10.3390/ijms21082987