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Signaling Pathways Potentially Responsible for Foam Cell Formation: Cholesterol Accumulation or Inflammatory Response—What is First?

Accumulation of lipid-laden (foam) cells in the arterial wall is known to be the earliest step in the pathogenesis of atherosclerosis. There is almost no doubt that atherogenic modified low-density lipoproteins (LDL) are the main sources of accumulating lipids in foam cells. Atherogenic modified LDL...

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Detalles Bibliográficos
Autores principales: Orekhov, Alexander N., Sukhorukov, Vasily N., Nikiforov, Nikita G., Kubekina, Marina V., Sobenin, Igor A., Foxx, Kathy K., Pintus, Sergey, Stegmaier, Philip, Stelmashenko, Daria, Kel, Alexander, Poznyak, Anastasia V., Wu, Wei-Kai, Kasianov, Artem S., Makeev, Vsevolod Y., Manabe, Ichiro, Oishi, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216009/
https://www.ncbi.nlm.nih.gov/pubmed/32295185
http://dx.doi.org/10.3390/ijms21082716