Use of 3D Human Liver Organoids to Predict Drug-Induced Phospholipidosis

Drug-induced phospholipidosis (PL) is a storage disorder caused by the formation of phospholipid-drug complexes in lysosomes. Because of the diversity of PL between species, human cell-based assays have been used to predict drug-induced PL in humans. We established three-dimensional (3D) human liver...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Young, Han, Hyo-Jeong, Lee, Sang-Joon, Cho, Eun-Ho, Lee, Han-Byul, Seok, Ju-Hyung, Lim, Hee Seon, Son, Woo-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216064/
https://www.ncbi.nlm.nih.gov/pubmed/32340283
http://dx.doi.org/10.3390/ijms21082982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216064/
https://www.ncbi.nlm.nih.gov/pubmed/32340283
http://dx.doi.org/10.3390/ijms21082982

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