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Loss of AMPKalpha1 Triggers Centrosome Amplification via PLK4 Upregulation in Mouse Embryonic Fibroblasts

Recent evidence indicates that activation of adenosine monophosphate-activated protein kinase (AMPK), a highly conserved sensor and modulator of cellular energy and redox, regulates cell mitosis. However, the underlying molecular mechanisms for AMPKα subunit regulation of chromosome segregation rema...

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Detalles Bibliográficos
Autores principales: Zhao, Qiang, Coughlan, Kathleen A, Zou, Ming-Hui, Song, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216113/
https://www.ncbi.nlm.nih.gov/pubmed/32316320
http://dx.doi.org/10.3390/ijms21082772