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PACAP Modulates the Autophagy Process in an In Vitro Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of complex etiology leading to motor neuron degeneration. Many gene alterations cause this pathology, including mutation in Cu, Zn superoxide dismutase (SOD1), which leads to its gain of function. Mutant SOD1 proteins are...

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Detalles Bibliográficos
Autores principales: D’Amico, Agata Grazia, Maugeri, Grazia, Saccone, Salvatore, Federico, Concetta, Cavallaro, Sebastiano, Reglodi, Dora, D’Agata, Velia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216177/
https://www.ncbi.nlm.nih.gov/pubmed/32331311
http://dx.doi.org/10.3390/ijms21082943