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Mechanical Properties of Human Bronchial Epithelial Cells Expressing Wt- and Mutant CFTR

Cystic fibrosis (CF) is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). A single recessive mutation, the deletion of phenylalanine 508 (F508del), causes severe CF and resides on 70% of mutant chromosomes. Disorganization of the actin cytoskele...

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Detalles Bibliográficos
Autores principales: Carapeto, Ana P., Vitorino, Miguel V., Santos, João D., Ramalho, Sofia S., Robalo, Tiago, Rodrigues, Mário S., Farinha, Carlos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216210/
https://www.ncbi.nlm.nih.gov/pubmed/32326361
http://dx.doi.org/10.3390/ijms21082916