C5-Substituted 2-Selenouridines Ensure Efficient Base Pairing with Guanosine; Consequences for Reading the NNG-3′ Synonymous mRNA Codons

5-Substituted 2-selenouridines (R5Se2U) are post-transcriptional modifications present in the first anticodon position of transfer RNA. Their functional role in the regulation of gene expression is elusive. Here, we present efficient syntheses of 5-methylaminomethyl-2-selenouridine (1, mnm5Se2U), 5-...

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Detalles Bibliográficos
Autores principales: Leszczynska, Grazyna, Cypryk, Marek, Gostynski, Bartlomiej, Sadowska, Klaudia, Herman, Paulina, Bujacz, Grzegorz, Lodyga-Chruscinska, Elzbieta, Sochacka, Elzbieta, Nawrot, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216251/
https://www.ncbi.nlm.nih.gov/pubmed/32326096
http://dx.doi.org/10.3390/ijms21082882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216251/
https://www.ncbi.nlm.nih.gov/pubmed/32326096
http://dx.doi.org/10.3390/ijms21082882

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