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C5-Substituted 2-Selenouridines Ensure Efficient Base Pairing with Guanosine; Consequences for Reading the NNG-3′ Synonymous mRNA Codons

5-Substituted 2-selenouridines (R5Se2U) are post-transcriptional modifications present in the first anticodon position of transfer RNA. Their functional role in the regulation of gene expression is elusive. Here, we present efficient syntheses of 5-methylaminomethyl-2-selenouridine (1, mnm5Se2U), 5-...

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Detalles Bibliográficos
Autores principales:	Leszczynska, Grazyna, Cypryk, Marek, Gostynski, Bartlomiej, Sadowska, Klaudia, Herman, Paulina, Bujacz, Grzegorz, Lodyga-Chruscinska, Elzbieta, Sochacka, Elzbieta, Nawrot, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216251/ https://www.ncbi.nlm.nih.gov/pubmed/32326096 http://dx.doi.org/10.3390/ijms21082882

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