A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye

The autoimmune disorder, Sjögren’s syndrome (SS), is characterized by lymphocytic infiltration and loss of function of exocrine glands such as the lacrimal gland (LG) and salivary gland. SS-associated changes in the LG are associated with the development of autoimmune-mediated dry eye disease. We ha...

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Detalles Bibliográficos
Autores principales: Hsueh, Pang-Yu, Ju, Yaping, Vega, Adrianna, Edman, Maria C., MacKay, J. Andrew, Hamm-Alvarez, Sarah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216292/
https://www.ncbi.nlm.nih.gov/pubmed/32326657
http://dx.doi.org/10.3390/ijms21082758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216292/
https://www.ncbi.nlm.nih.gov/pubmed/32326657
http://dx.doi.org/10.3390/ijms21082758

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