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A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye
The autoimmune disorder, Sjögren’s syndrome (SS), is characterized by lymphocytic infiltration and loss of function of exocrine glands such as the lacrimal gland (LG) and salivary gland. SS-associated changes in the LG are associated with the development of autoimmune-mediated dry eye disease. We ha...
Autores principales: | Hsueh, Pang-Yu, Ju, Yaping, Vega, Adrianna, Edman, Maria C., MacKay, J. Andrew, Hamm-Alvarez, Sarah F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216292/ https://www.ncbi.nlm.nih.gov/pubmed/32326657 http://dx.doi.org/10.3390/ijms21082758 |
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