Cargando…

Detrimental role of sphingosine kinase 1 in kidney damage in DOCA-salt hypertensive model: evidence from knockout mice

BACKGROUND: Sphingosine-1-phosphate (S1P) is a bioactive metabolite of sphingolipids and produced by sphingosine kinases (SphK1 and SphK2). SphK1/S1P pathway is implicated in the progression of chronic kidney disease. However, the role of SphK1/S1P pathway in renal injury in hypertension has not bee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lyu, Bingqing, Wang, Weili, Ji, Xin-Ying, Ritter, Joseph K., Li, Ningjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216348/ https://www.ncbi.nlm.nih.gov/pubmed/32393187 http://dx.doi.org/10.1186/s12882-020-01815-8

Ejemplares similares

Mycophenolate Mofetil Attenuates DOCA-Salt Hypertension: Effects on Vascular Tone
por: Moes, Arthur D., et al.
Publicado: (2018)

Serelaxin improves cardiac and renal function in DOCA-salt hypertensive rats
por: Wang, Dong, et al.
Publicado: (2017)

Evidence of Cardiovascular Calcification and Fibrosis in Pseudoxanthoma Elasticum Mouse Models Subjected to DOCA-Salt Hypertension
por: Omarjee, Loukman, et al.
Publicado: (2019)

Effect of Scurrula atropurpurea on nitric oxide, endothelial damage, and endothelial progenitor cells of DOCA-salt hypertensive rats
por: Athiroh, Nour, et al.
Publicado: (2014)

The DOCA-Salt Hypertensive Rat as a Model of Cardiovascular Oxidative and Inflammatory Stress
por: Iyer, Abishek, et al.
Publicado: (2010)

Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats
por: Imenshahidi, Mohsen, et al.
Publicado: (2014)

Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension
por: Amaral, Jefferson H., et al.
Publicado: (2015)

Collecting Duct Renin Does Not Mediate DOCA-Salt Hypertension or Renal Injury
por: Song, Kai, et al.
Publicado: (2016)

EFFECTS OF CHRONIC EXCESS SALT INGESTION : ROLE OF GENETIC FACTORS IN BOTH DOCA-SALT AND RENAL HYPERTENSION
por: Dahl, Lewis K., et al.
Publicado: (1963)

α-MSH Analogue Attenuates Blood Pressure Elevation in DOCA-Salt Hypertensive Mice
por: Rinne, Petteri, et al.
Publicado: (2013)

Modulatory effect of sesamol on DOCA-salt-induced oxidative stress in uninephrectomized hypertensive rats
por: Hemalatha, Govindasamy, et al.
Publicado: (2013)

Renoprotective Effect of the Histone Deacetylase Inhibitor CG200745 in DOCA-Salt Hypertensive Rats
por: Bae, Eun Hui, et al.
Publicado: (2019)

Nitrooleic Acid Attenuates Lipid Metabolic Disorders and Liver Steatosis in DOCA-Salt Hypertensive Mice
por: Wang, Haiping, et al.
Publicado: (2015)

PGC-1α overexpression suppresses blood pressure elevation in DOCA-salt hypertensive mice
por: Zhao, Qingbin, et al.
Publicado: (2015)

Captopril Alleviates Chondrocyte Senescence in DOCA-Salt Hypertensive Rats Associated with Gut Microbiome Alteration
por: Chan, Lok Chun, et al.
Publicado: (2022)

Mycophenolate Improves Brain–Gut Axis Inducing Remodeling of Gut Microbiota in DOCA-Salt Hypertensive Rats
por: Robles-Vera, Iñaki, et al.
Publicado: (2020)

Cardiac Natriuretic Peptide Profiles in Chronic Hypertension by Single or Sequentially Combined Renovascular and DOCA-Salt Treatments
por: Cerrudo, Carolina S., et al.
Publicado: (2021)

Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats
por: Robles-Vera, Iñaki, et al.
Publicado: (2021)

Adipose Mesenchymal Cells-Derived EVs Alleviate DOCA-Salt-Induced Hypertension by Promoting Cardio-Renal Protection
por: Lindoso, Rafael Soares, et al.
Publicado: (2019)

Activation of the Renal PI3K/Akt/mTOR Signaling Pathway in a DOCA-Salt Model of Hypertension
por: Ma, Seong Kwon, et al.
Publicado: (2012)

ROS Suppression by Egg White Hydrolysate in DOCA-Salt Rats—An Alternative Tool against Vascular Dysfunction in Severe Hypertension
por: Abreu, Edina da Luz, et al.
Publicado: (2022)

Role of aspirin activated nitric oxide synthase in controlling DOCA-salt-induced hypertension in rats through the stimulation of renal r-cortexin in kidney cortex cells
por: Maji, Uttam Kumar, et al.
Publicado: (2022)

Arterial expression of 5-HT(2B )and 5-HT(1B )receptors during development of DOCA-salt hypertension
por: Banes, Amy KL, et al.
Publicado: (2003)

Long-Term Inhibition of Xanthine Oxidase by Febuxostat Does Not Decrease Blood Pressure in Deoxycorticosterone Acetate (DOCA)-Salt Hypertensive Rats
por: Szasz, Theodora, et al.
Publicado: (2013)

Myeloid Angiotensin II Type 1 Receptor Mediates Macrophage Polarization and Promotes Vascular Injury in DOCA/Salt Hypertensive Mice
por: Yang, Xue-Feng, et al.
Publicado: (2022)

Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models
por: Tauber, Philipp, et al.
Publicado: (2021)

Brain endogenous angiotensin II receptor type 2 (AT2-R) protects against DOCA/salt-induced hypertension in female rats
por: Dai, Shu-Yan, et al.
Publicado: (2015)

Interaction of central Angiotensin II and estrogen on systolic blood pressure in female DOCA-salt treated rats
por: Kafami, Marzieh, et al.
Publicado: (2016)

Commentary: The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension
por: Bhavanam, Naga P., et al.
Publicado: (2015)

Histone deacetylase inhibitor, CG200745, attenuates cardiac hypertrophy and fibrosis in DOCA-induced hypertensive rats
por: Lee, Eunjo, et al.
Publicado: (2016)

LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism
por: Flahault, Adrien, et al.
Publicado: (2021)

Dietary Protein, Chronic Salt-Sensitive Hypertension, and Kidney Damage
por: Mattson, David L., et al.
Publicado: (2023)

Sphingosine Kinase 2 Knockout Mice Resist HFD-Induced Obesity Through Increasing Energy Expenditure
por: Zhao, Jiawei, et al.
Publicado: (2023)

Chronic Blockade of Brain Endothelin Receptor Type-A (ET(A)) Reduces Blood Pressure and Prevents Catecholaminergic Overactivity in the Right Olfactory Bulb of DOCA-Salt Hypertensive Rats
por: Cassinotti, Luis R., et al.
Publicado: (2018)

Drugging Sphingosine Kinases
por: Santos, Webster L., et al.
Publicado: (2014)

Hypertension and Dementia: Epidemiological and Experimental Evidence Revealing a Detrimental Relationship
por: Perrotta, Marialuisa, et al.
Publicado: (2016)

Sphingosine Kinase 1 and Sphingosine-1-Phosphate Signaling in Colorectal Cancer
por: Bao, Yonghua, et al.
Publicado: (2017)

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Role of opioid signaling in kidney damage during the development of salt-induced hypertension
por: Golosova, Daria, et al.
Publicado: (2020)

Natural sea salt consumption confers protection against hypertension and kidney damage in Dahl salt-sensitive rats
por: Lee, Bog-Hieu, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_501hg496hmvudhnkuebjh1g3hl