Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis

BACKGROUND: A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity. EOC spheroids are subjected to bioenergetic stress, thereby activating AMP-activated protein kina...

Descripción completa

Detalles Bibliográficos
Autores principales: Laski, Jeremi, Singha, Bipradeb, Wang, Xu, Valdés, Yudith Ramos, Collins, Olga, Shepherd, Trevor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216359/
https://www.ncbi.nlm.nih.gov/pubmed/32393385
http://dx.doi.org/10.1186/s13048-020-00660-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216359/
https://www.ncbi.nlm.nih.gov/pubmed/32393385
http://dx.doi.org/10.1186/s13048-020-00660-5

Ejemplares similares