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Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling pathway in spinal microglia

BACKGROUND: Neuroinflammation plays a vital role in the development and maintenance of neuropathic pain. Recent evidence has proved that bone marrow mesenchymal stem cells (BMSCs) can inhibit neuropathic pain and possess potent immunomodulatory and immunosuppressive properties via secreting a variet...

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Detalles Bibliográficos
Autores principales: Yang, Hao, Wu, Lingmin, Deng, Huimin, Chen, Yuanli, Zhou, Huanping, Liu, Meiyun, Wang, Shaochen, Zheng, Li, Zhu, Lina, Lv, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216552/
https://www.ncbi.nlm.nih.gov/pubmed/32393298
http://dx.doi.org/10.1186/s12974-020-1731-x