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Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling pathway in spinal microglia
BACKGROUND: Neuroinflammation plays a vital role in the development and maintenance of neuropathic pain. Recent evidence has proved that bone marrow mesenchymal stem cells (BMSCs) can inhibit neuropathic pain and possess potent immunomodulatory and immunosuppressive properties via secreting a variet...
Autores principales: | Yang, Hao, Wu, Lingmin, Deng, Huimin, Chen, Yuanli, Zhou, Huanping, Liu, Meiyun, Wang, Shaochen, Zheng, Li, Zhu, Lina, Lv, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216552/ https://www.ncbi.nlm.nih.gov/pubmed/32393298 http://dx.doi.org/10.1186/s12974-020-1731-x |
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