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Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways

Background: Histones could be released from the nucleus when stimulated. Increasing evidence has shown that extracellular histones are associated with a variety of inflammation and diseases. Nucleotide binding oligomerzation domain 2 (NOD2) belongs to the NOD like receptor (NLR) family and is report...

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Detalles Bibliográficos
Autores principales: Shi, Chun-xia, Wang, Yao, Chen, Qian, Jiao, Fang-zhou, Pei, Mao-hua, Gong, Zuo-jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216582/
https://www.ncbi.nlm.nih.gov/pubmed/32432055
http://dx.doi.org/10.3389/fcimb.2020.00196