1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain

Chronic pain can be the result of an underlying disease or condition, medical treatment, inflammation, or injury. The number of persons experiencing this type of pain is substantial, affecting upwards of 50 million adults in the United States. Pharmacotherapy of most of the severe chronic pain patie...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan, Cai, Song, Gomez, Kimberly, Wijeratne, E. M. Kithsiri, Ji, Yingshi, Bellampalli, Shreya S., Luo, Shizhen, Moutal, Aubin, Gunatilaka, A. A. Leslie, Khanna, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216607/
https://www.ncbi.nlm.nih.gov/pubmed/32393368
http://dx.doi.org/10.1186/s13041-020-00616-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216607/
https://www.ncbi.nlm.nih.gov/pubmed/32393368
http://dx.doi.org/10.1186/s13041-020-00616-2

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