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Fluoroquinolone resistance and mutational profile of gyrA in pulmonary MDR tuberculosis patients

BACKGROUND: Fluoroquinolones (FQs) are potential drugs that inhibit DNA synthesis and are used in the treatment of multidrug-resistant tuberculosis (TB) and short-term anti-TB regimens. In recent years, a high proportion of FQ resistance has been observed in Mycobacterium tuberculosis isolates. The...

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Detalles Bibliográficos
Autores principales: Kabir, Saba, Tahir, Zarfishan, Mukhtar, Nadia, Sohail, Muhammad, Saqalein, Muhammad, Rehman, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216623/
https://www.ncbi.nlm.nih.gov/pubmed/32393213
http://dx.doi.org/10.1186/s12890-020-1172-4