Metabolic remodeling during somatic cell reprogramming to induced pluripotent stem cells: involvement of hypoxia-inducible factor 1

Induced pluripotent stem cells (iPSCs) were first established from differentiated somatic cells by gene introduction of key transcription factors, OCT4, SOX2, KLF4, and c-MYC, over a decade ago. Although iPSCs can be applicable for regenerative medicine, disease modeling and drug screening, several...

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Detalles Bibliográficos
Autores principales: Ishida, Tomoaki, Nakao, Shu, Ueyama, Tomoe, Harada, Yukihiro, Kawamura, Teruhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216665/
https://www.ncbi.nlm.nih.gov/pubmed/32426078
http://dx.doi.org/10.1186/s41232-020-00117-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216665/
https://www.ncbi.nlm.nih.gov/pubmed/32426078
http://dx.doi.org/10.1186/s41232-020-00117-8

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