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Metabolic remodeling during somatic cell reprogramming to induced pluripotent stem cells: involvement of hypoxia-inducible factor 1

Induced pluripotent stem cells (iPSCs) were first established from differentiated somatic cells by gene introduction of key transcription factors, OCT4, SOX2, KLF4, and c-MYC, over a decade ago. Although iPSCs can be applicable for regenerative medicine, disease modeling and drug screening, several...

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Detalles Bibliográficos
Autores principales:	Ishida, Tomoaki, Nakao, Shu, Ueyama, Tomoe, Harada, Yukihiro, Kawamura, Teruhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216665/ https://www.ncbi.nlm.nih.gov/pubmed/32426078 http://dx.doi.org/10.1186/s41232-020-00117-8

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