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A powerful microbial group association test based on the higher criticism analysis for sparse microbial association signals

BACKGROUND: In human microbiome studies, it is crucial to evaluate the association between microbial group (e.g., community or clade) composition and a host phenotype of interest. In response, a number of microbial group association tests have been proposed, which account for the unique features of...

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Detalles Bibliográficos
Autores principales: Koh, Hyunwook, Zhao, Ni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216722/
https://www.ncbi.nlm.nih.gov/pubmed/32393397
http://dx.doi.org/10.1186/s40168-020-00834-9