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Beneficial impact of epigallocatechingallate on LDL-C through PCSK9/LDLR pathway by blocking HNF1α and activating FoxO3a

BACKGROUND: Green tea drinking has been proven to lower lipid and exert cardiovascular protection, while the potential mechanism has not been fully determined. This study was to investigate whether the beneficial impact of epigallocatechingallate (EGCG), a type of catechin in green tea on lipids is...

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Detalles Bibliográficos
Autores principales: Cui, Chuan-Jue, Jin, Jing-Lu, Guo, Lin-Na, Sun, Jing, Wu, Na-Qiong, Guo, Yuan-Lin, Liu, Geng, Dong, Qian, Li, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216725/
https://www.ncbi.nlm.nih.gov/pubmed/32398139
http://dx.doi.org/10.1186/s12967-020-02362-4