Translational regulation of periplasmic folding assistants and proteases as a valuable strategy to improve production of translocated recombinant proteins in Escherichia coli

BACKGROUND: Advantages of translocation of recombinant proteins to the periplasm in Escherichia coli include simplified downstream processing, and improved folding and in vivo activity of the target protein. There are, however, problems encountered in the periplasmic production that can be associate...

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Detalles Bibliográficos
Autores principales: Gawin, Agnieszka, Ertesvåg, Helga, Hansen, Sine Alise Hartvigsen, Malmo, Jostein, Brautaset, Trygve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216727/
https://www.ncbi.nlm.nih.gov/pubmed/32393331
http://dx.doi.org/10.1186/s12896-020-00615-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216727/
https://www.ncbi.nlm.nih.gov/pubmed/32393331
http://dx.doi.org/10.1186/s12896-020-00615-0

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