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Melatonin-Induced PGC-1α Improves Angiogenic Potential of Mesenchymal Stem Cells in Hindlimb Ischemia

Despite the therapeutic effect of mesenchymal stem cells (MSCs) in ischemic diseases, pathophysiological conditions, including hypoxia, limited nutrient availability, and oxidative stress restrict their potential. To address this issue, we investigated the effect of melatonin on the bioactivities of...

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Detalles Bibliográficos
Autores principales: Lee, Jun Hee, Han, Yong-Seok, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216743/
https://www.ncbi.nlm.nih.gov/pubmed/31739381
http://dx.doi.org/10.4062/biomolther.2019.131