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Spinosin Inhibits Aβ(1-42) Production and Aggregation via Activating Nrf2/HO-1 Pathway

The present research work primarily investigated whether spinosin has the potential of improving the pathogenesis of Alzheimer’s disease (AD) driven by β-amyloid (Aβ) overproduction through impacting the procession of amyloid precursor protein (APP). Wild type mouse Neuro-2a cells (N2a/WT) and N2a s...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoying, Wang, Jinyu, Gong, Guowei, Ma, Ruixin, Xu, Fanxing, Yan, Tingxu, Wu, Bo, Jia, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216747/
https://www.ncbi.nlm.nih.gov/pubmed/31791116
http://dx.doi.org/10.4062/biomolther.2019.123