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Spinosin Inhibits Aβ(1-42) Production and Aggregation via Activating Nrf2/HO-1 Pathway
The present research work primarily investigated whether spinosin has the potential of improving the pathogenesis of Alzheimer’s disease (AD) driven by β-amyloid (Aβ) overproduction through impacting the procession of amyloid precursor protein (APP). Wild type mouse Neuro-2a cells (N2a/WT) and N2a s...
Autores principales: | Zhang, Xiaoying, Wang, Jinyu, Gong, Guowei, Ma, Ruixin, Xu, Fanxing, Yan, Tingxu, Wu, Bo, Jia, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216747/ https://www.ncbi.nlm.nih.gov/pubmed/31791116 http://dx.doi.org/10.4062/biomolther.2019.123 |
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