Investigating the Causal Effect of Brain Expression of CCL2, NFKB1, MAPK14, TNFRSF1A, CXCL10 Genes on Multiple Sclerosis: A Two-Sample Mendelian Randomization Approach

Multiple Sclerosis (MS) exhibits considerable heterogeneity in phenotypic expression, course, prognosis and response to therapy. This suggests this disease involves multiple, as yet poorly understood, causal mechanisms. In this work we assessed the possible causal link between gene expression level...

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Detalles Bibliográficos
Autores principales: Fazia, Teresa, Nova, Andrea, Gentilini, Davide, Beecham, Ashley, Piras, Marialuisa, Saddi, Valeria, Ticca, Anna, Bitti, Pierpaolo, McCauley, Jacob L., Berzuini, Carlo, Bernardinelli, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216783/
https://www.ncbi.nlm.nih.gov/pubmed/32432099
http://dx.doi.org/10.3389/fbioe.2020.00397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216783/
https://www.ncbi.nlm.nih.gov/pubmed/32432099
http://dx.doi.org/10.3389/fbioe.2020.00397

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