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Understanding the challenge of comparative effectiveness research in focal epilepsy: A review of network meta‐analyses and real‐world evidence on antiepileptic drugs

OBJECTIVE: Head‐to‐head randomized controlled trials (RCTs) are the gold standard for assessing comparative treatment effects. In the absence of direct comparisons between all possible antiepileptic drugs (AEDs), however, clinical decision‐making in focal (partial onset) epilepsy relies on alternati...

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Detalles Bibliográficos
Autores principales: Thieffry, Solène, Klein, Pavel, Baulac, Michel, Plumb, Jonathan, Pelgrims, Barbara, Steeves, Sara, Borghs, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216985/
https://www.ncbi.nlm.nih.gov/pubmed/32201951
http://dx.doi.org/10.1111/epi.16476