Real‐Time BODIPY‐Binding Assay To Screen Inhibitors of the Early Oligomerization Process of Aβ1–42 Peptide

Misfolding and aggregation of amyloid β1–42 peptide (Aβ1–42) play a central role in the pathogenesis of Alzheimer's disease (AD). Targeting the highly cytotoxic oligomeric species formed during the early stages of the aggregation process represents a promising therapeutic strategy to reduce the...

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Detalles Bibliográficos
Autores principales: Tonali, Nicolo, Dodero, Veronica I., Kaffy, Julia, Hericks, Loreen, Ongeri, Sandrine, Sewald, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217026/
https://www.ncbi.nlm.nih.gov/pubmed/31702868
http://dx.doi.org/10.1002/cbic.201900652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217026/
https://www.ncbi.nlm.nih.gov/pubmed/31702868
http://dx.doi.org/10.1002/cbic.201900652

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