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Tumor genetic heterogeneity analysis of chronic sun‐damaged melanoma

Chronic sun‐damaged (CSD) melanoma represents 10%–20% of cutaneous melanomas and is characterized by infrequent BRAF V600E mutations and high mutational load. However, the order of genetic events or the extent of intra‐tumor heterogeneity (ITH) in CSD(high) melanoma is still unknown. Ultra‐deep targ...

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Detalles Bibliográficos
Autores principales: Sanna, Adriana, Harbst, Katja, Johansson, Iva, Christensen, Gustav, Lauss, Martin, Mitra, Shamik, Rosengren, Frida, Häkkinen, Jari, Vallon‐Christersson, Johan, Olsson, Håkan, Ingvar, Åsa, Isaksson, Karolin, Ingvar, Christian, Nielsen, Kari, Jönsson, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217060/
https://www.ncbi.nlm.nih.gov/pubmed/31811783
http://dx.doi.org/10.1111/pcmr.12851