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CD4(+) T Cells at the Center of Inflammaging
Bharath et al., 2020 report that CD4(+) T lymphocytes from aged individuals exhibit defective mitochondrial autophagy, resulting in altered redox metabolism and upregulation of TH17 cytokines, which in turn may contribute to aging-associated chronic inflammation or “inflammaging.” Of note, the antia...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217078/ https://www.ncbi.nlm.nih.gov/pubmed/32402265 http://dx.doi.org/10.1016/j.cmet.2020.04.016 |