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Synthesis, Modification, and Biological Evaluation of a Library of Novel Water‐Soluble Thiopyridone‐Based Organometallic Complexes and Their Unexpected (Biological) Behavior

A series of 16 dinuclear thiopyridone‐based organometallics with excellent water solubility, increased stability and remarkable cytotoxicity were synthesized and characterized. The complexes of this work formed dimeric species featuring a double positive charge in polar protic solvents, accounting f...

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Detalles Bibliográficos
Autores principales: Harringer, Sophia, Happl, Barbara, Ozenil, Marius, Kast, Caroline, Hejl, Michaela, Wernitznig, Debora, Legin, Anton A., Schweikert, Andreas, Gajic, Natalie, Roller, Alexander, Koellensperger, Gunda, Jakupec, Michael A., Kandioller, Wolfgang, Keppler, Bernhard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217150/
https://www.ncbi.nlm.nih.gov/pubmed/31958176
http://dx.doi.org/10.1002/chem.201905546